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"We have developed a novel approach for the detection of MRI based on optical atomic magnetometry," said chemist Alexander Pines, one of the world's leading authorities on NMR/MRI technology and leader of the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) team. Pines holds a joint appointment as a chemist with Berkeley Lab's Materials Sciences Div. and with UC Berkeley, where he is the Glenn T. Seaborg Professor of Chemistry. "Our technique provides a viable alternative for MRI detection with substantially enhanced sensitivity and time resolution for various situations where traditional MRI is not optimal."
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The identification of particular molecular interactions therefore has been a crucial first step in many cellular studies. Traditionally, biochemical techniques have proven to be an effective indicator of interactions between two proteins of interest. These techniques are almost always limited to in vitro studies, however. More recently, technological advances in fluorescence microscopy and fluo...
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